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Poly(2-hydroxyethyl methacrylate)

Catalog number Type Package size Price, USD
30661-100 poly(2-HEMA) 10 g 200.00
30661-101 poly(2-HEMA-co-MAA) [90:10] 10 g 250.00

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Product Details


Handle with normal care.


Store at room temperature our of direct sunlight.

Molecular weight

Mn: 3-10 kDa (size exclusion chromatography, PEG/PEO standards)


Poly(2-Hydroxyethyl methacrylate) (pHEMA) is biocompatible hydrophilic methacrylate polymer. In the dry state the material is hard and glassy, but in polar media the pendant hydroxyethyl group is able to extent outward and the material becomes soft and flexible. pHEMA is soluble in common organic polar solvents such as lower alcohols, however the polymer will not dissolve in water without a co-solvent, but instead it will absorb water and swell.

Due to its good biocompatibility pHEMA has been extensively researched for biomedical applications such as hydrogel systems for drug delivery or scaffolds for tissue engineering. The most prominent example of a biomedical device based on pHEMA may be the very first modern soft contact lenses developed by Otto Wichterle around 1960. To this day, the monomeric unit (2-hydroxyethyl methacrylate) is still a key component of many soft contact lens systems.

pHEMA may also find usage in coating applications to change the surface properties of a substrate. For example, pHEMA is commonly used to coat culture vessels in order to prevent cell adhesion or favor the formation of spheroidal cells.

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